Abstract
ObjectiveCerebral vasospasm can occur after skull base tumor removal. Few studies concentrated on the posterior circulation vasospasm after tumor resection in the posterior fossa. We aimed to identify the risk factors associated with postoperative vertebrobasilar vasospasm after tumor resection in the foramen magnum.MethodsWe retrospectively reviewed the data of 62 patients with tumors in the foramen magnum at our institution from January 2010 to January 2015. The demographic data, tumor features, surgical characteristics were collected. Vertebrobasilar vasospasm was evaluated by bedside transcranial Doppler before surgery and on postoperative day 1, 3, 7. Univariate and multivariate analyses were performed to determine the predictors of postoperative vasospasm in the posterior circulation.ResultsVertebrobasilar vasospasm was detected in 28 (53.8%) of the 62 patients at a mean time of 3.5 days after surgery. There were 5 (8%) patients with severe vasospasm according to the grading criteria. Age, tumor type, tumor size, vertebral artery encasement, and surgical time were significantly related to vasospasm in the univariate analysis. Further multivariate analysis demonstrated that only age and vertebral artery encasement were independent risk factors predicting the occurrence of postoperative vertebrobasilar vasospasm.ConclusionsThe incidence of acute vertebrobasilar vasospasm is not uncommon after foramen magnum tumor resection. Age and vertebral artery encasement are significantly correlated with postoperative vasospasm. Close monitoring of vasospasm should be given to patients with younger age and the presence of vertebral artery encasement on the preoperative imaging to facilitate early diagnosis and intervention.
Highlights
Cerebral vasospasm is a common sequela after subarachnoid hemorrhage due to an aneurysmal rupture or neurotrauma[1, 2]
Further multivariate analysis demonstrated that only age and vertebral artery encasement were independent risk factors predicting the occurrence of postoperative vertebrobasilar vasospasm
Age and vertebral artery encasement are significantly correlated with postoperative vasospasm
Summary
Cerebral vasospasm is a common sequela after subarachnoid hemorrhage due to an aneurysmal rupture or neurotrauma[1, 2]. It can occur following brain tumor resection, especially after skull base tumor removal[3,4,5,6,7]. More than half of acoustic neuromas removal were reported to produce cerebral vasospasm[6]. This implies that the occurrence of vasospasm after tumor resection in the posterior fossa may be underestimated previously[6]
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