Abstract
THE SPECTRUM of resultant defects for early amnion rupture has been expanded to include defects other than those caused by amniotic band disruption per se. These include craniofacial defects, limb reduction defects, cutaneous syndactyly, body wall deficiency, a short umbilical cord, scoliosis, and growth deficiency. 1-~ The nature of these additional defects is thought to relate to early intrauterine compression of the embryo resulting from at least a temporary loss of amniotic fluid. Support for this hypothesis derives from experimental studies in rats, in which the same duster of anomalies is induced by early amnion puncture at a time equivalent to four to six weeks in the human. 6 The purpose of this communication is to report yet another potential consequence of early amnion rupture, namely, a rare form of preaxial polydactyly of the foot, observed in two unrelated patients who had evidence of early amnion rupture.
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