Abstract
More than 50 million people worldwide have epilepsy.1 About two-thirds of them are well-controlled on 1 or 2 appropriately used antiepileptic drugs (AEDs).2 One-third of patients with epilepsy remain refractory to medications, and experience seizures despite a complex regimen of multiple drugs. Some patients may be candidates for surgical interventions, either curative or palliative. Many times in clinical practice the question arises as to whether a patient is a candidate for withdrawing AEDs, either because the epilepsy is well-controlled medically or because the patient became seizure-free after surgery.
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