Abstract

and circumference (10.7±0.9mm vs. NS 8.5±0.9mm and LCT 9.0±0.9mm, p < 0.001). Although there were no differences in jejunal length, villus height, villus width or crypt width, mucosal-to-serosal amplification ratio calculations revealed greater jejunal mucosal surface area with MCT (327±77cm2 vs. NS 193±85cm2 and LCT 215±40cm2, p < 0.01). Conclusion: MCT appear superior to NS and LCT in increasing jejunal gross morphology and mucosal surface area after massive ileocecal resection, independent of enteric hormones. It remains to be determined whether MCT can stimulate functional adaptation of remnant jejunum in SBS.

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