Abstract
Diabetes is one of the most dangerous metabolic disorders, with high rates of mortality worldwide. Since ancient times, medicinal plants have been used in traditional medicine to treat many diseases, including diabetes and its related complications. Plants are widely accepted, affordable, and perceived to have minimal adverse side effects. The Lamiaceae family is a potential source of therapeutic agents for the management of metabolic disorders, including diabetes. Hence, this review paper summarizes the antidiabetic use of Lamiaceae species in folk medicine globally. Furthermore, we present the antidiabetic activities and phytochemical constituents of twenty-three (23) Lamiaceae species and the antidiabetic activity of some notable chemical constituents isolated from some of these Lamiaceae species.
Highlights
Species in the Management of Diabetes mellitus (DM) is one of the most dangerous metabolic disorders, causing high mortality rates worldwide [1]
Salvia officinalis is native to the Southern Europe and Mediterranean areas; it is a perennial round shrub widely naturalized throughout the world [122]
S. officinalis has been demonstrated to be as powerful as metformin, a well-known oral antidiabetic drug utilized for the treatment of type 2 diabetes [123]
Summary
Species in the Management of Diabetes mellitus (DM) is one of the most dangerous metabolic disorders, causing high mortality rates worldwide [1]. Many synthetic antidiabetic drugs such as acarbose, sulfonylurea, miglitol, metformin, and thiazolidinedione are already present in the market Their effectiveness is restricted because of their high cost and adverse side effects [7,8], which incentivize the development of powerful natural antidiabetic products/drugs with minimal adverse side effects. The family possesses significant economic value, as it contains some horticultural species and culinary herbs, such as rosemary, salvia, ocimum, and leonotis. They are well reputed because of the high level of aromatic compounds within their leaves, flowers, and essential oils. These compounds are pharmacologically active terpenoids that play vital roles in developing new bioactive products within the cosmeceuticals, nutraceuticals, Diabetes.
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