Abstract
A case of postural hypotension due to urinary salt wasting is presented. Subnormal aldosterone excretion rates in response to salt depletion, hypotension and angiotensin infusion was demonstrated, with apparently normal renal, adrenal and pituitary function. The hemodynamic patterns of hypovolemia, particularly a reduction in central blood volume and consequent hypotension associated with tilting, was observed. Therapy with supplemental sodium chloride relieved the patient's symptoms but became unnecessary when her weight returned to the presymptomatic level.
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