Abstract
A great controversy has emerged recently regarding the effectiveness of unconventional therapies such as: bariatric surgery, intermittent fasting and their ability to cure type 2 diabetes versus the conventional approaches that accompany diabetic patient throughout his life with the need for a therapeutic escalation. Nevertheless, three facts are missing in this approach, the first is the little step back with it especially on the cardiovascular prognosis and the second is the application on pathology such as type2 diabetes so heterogeneous that the therapeutic response can’t be extrapolates. Finally, what is the frequency and severity of subsequent recurrences of diabetes? And will this approach still be as effective? Hence the interest of taking into account two essential aspects before starting this process, the genetic status that modulates the therapeutic response whether for the classical or contemporary approach and which will be necessary to establish a score in order to select the responders to this approach. And vitamin status especially since this new therapeutic method is based primarily on weight loss and all that goes with vitamin losses that may trigger a cascade of subclinical atherosclerosis maintained despite the reversibility of diabetes.
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