Population genomics reveals that a missense mutation in EDNRB2 contributes to white plumage color in pigeons

Abstract

Plumage color is an important economic trait for breed feature identification and consumer's requirement in pigeons. The domestic pigeon has multiple type of plumage color, thereby providing a unique opportunity for identify the genetic basis of plumage coloration. White feather color is common for meat and medicinal use. To investigate the genetic variation associated with white plumage color in pigeons, we use genome resequencing and population genomics to identify the genomic regions with strong selective signature between pigeons with brown and white plumage color. Meanwhile, we obtained some candidate genes with melanin or melanosome biosynthesis in selected region. Finally, we identified a missense mutation p.E256K in the EDNRB2 completely associated with white plumage color. These findings provide a basis for genetic variation in pigeons with plumage color phenotype.