Abstract
X- Short Tandem Repeats (X-STRs) can be useful tool in forensic casework. In order to implement X-STR typing into routine forensic practice, reference database of a given population should be established.In this study, we examined 191 (91 female, 100 male) samples taken from unrelated healthy people living in Turkey with the Investigator Argus X-12 kit (Qiagen, Germany) which detects 12 X-STR markers.All loci in female individuals were consistent with the Hardy- Weinberg equilibrium test. The combined power of discrimination values in male and female individuals was 0.9999999994 and 0.9999999999, respectively. The most polymorphic locus was DXS10135 with 24 alleles while the least polymorphic locus was DXS8378 with 5 alleles. The haplotype diversity was found to be greater than 0.99 for all Linkage Groups (LGs).Finally, genetic distance analysis showed low significant differences between this population, and neighboring country populations.The results of this study suggest these 12 X-STRs markers are suitable to be used in forensic genetics and that Turkish population is a genetically low level differentiated population from neighboring countries.
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