Abstract
The polypeptides in TIV and in TIV-infected hemocytes were studied by polyacrylamide gel electrophoresis (PAGE). TIV consists of 28 polypeptides ranging in molecular weight from 17,500 to 300,000. The lowest molecular weight polypeptide appears to be a lipoprotein, and none appear to be glycoproteins. Proteins, banding in the same area as TIV polypeptides, are seen in gels after PAGE of hemocytes from larvae 4 hr after viral injection. Also present in infected cells are 6 noncapsid viral polypetides. Infection by TIV is accompanied by an immediate depression of leucine incorporation into hemocyte and plasma proteins and a switch in synthesis from host-specific to virus-specific polypeptides.
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