Abstract

Result: The PK and PD were similar between treatments, with the 90% CI for the ratios of geometric least squares means completely contained in the prespecified bioequivalence limit of 0.80-1.25 (Table). Adverse events were similar for LY IGlar and IGlar. No safety concernswere noted in clinical laboratory, vital signs, or ECG data. Conclusion: These studies demonstrate similarity in the PK and PD properties of LY IGlar and IGlar.

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