Abstract
This review presents the actual data about structure, genetic diversity and pathogenicity factors of human respiratory syncytial virus (hRSv) and human metapneumovirus - which are the members of new Pneumoviridae family, according to updated taxonomy accepted by the International Committee on Taxonomy of Viruses (ICTV) in 2016. The results of own epidemiological and clinical studies are presented in comparison with literature data. Cyclic recurrence of hRSv circulation was revealed. The clinical and epidemiological characteristics of hRSv and hMpv infections were compared. The leading role of the hRSv in ARVI in children and the importance of hMpv as an etiological agent of respiratory infection in adults are shown. Significance of both viruses as the agents of the lower respiratory tract infections is emphasized. The factors contributing to the prevalence of the hRSv in children with ARI are analyzed. Prevention measures for these infections are considered.
Highlights
This review presents the actual data about structure, genetic diversity and pathogenicity factors of human respiratory syncytial virus and human metapneumovirus — which are the mem bers of new Pneumoviridae family, according to updated taxonomy accepted by the International Committee on Taxonomy o f Viruses (ICTV) in 2016
The results o f own epidemiological and clinical studies are presented in comparison with literature data
The factors contribut ing to the prevalence o fthe human respiratory syncytial virus (hRSv) in children with ARI are analyzed
Summary
В обзоре даны современные сведения о строении, генетическом разнообразии и факторах патогенности пневмовирусов — респираторно-синцитиального вируса чело века (PC-вируса) и метапневмовируса человека, в связи с образованием нового семейства Pneumoviridae по решению международного совета по таксономии вирусов в 2016 году. Представлены результаты собственных клинико-эпидемиологических исследований в сравнении с данными литературы. Проведено сравнение клинико-эпидемиологических характеристик данных инфек ций. Показана лидирующая роль PC-вируса при ОРВИ детей и значимость мета пневмовируса как этиологического агента респираторной инфекции взрослых. Подчеркивается важная роль обоих вирусов в развитии инфекций нижних отделов ды хательных путей. Проанализированы факторы, способствующие широкой распростра ненности PC-вируса у больных ОРЗ детей. Ключевые слова: респираторная инфекция, респираторно-синцитиальный вирус, метап невмовирус, эпидемиология
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of microbiology, epidemiology and immunobiology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
