PMH25 HEALTH CARE USE AND COSTS OF PATIENTS WITH “PURE OBSESSIVE-COMPULSIVE DISORDER” VERSUS “PURE DEPRESSION”: 9-YEAR (1997-2006), LARGE-SCALE, RETROSPECTIVE CLAIMS ANALYSIS OF FLORIDA MEDICAID ADULT ENROLLEES

Abstract

A COMPARISION OF HEALTH CARE UTILIZATION AND COST OF CHILDREN ANDADOLESCENTSWITH BIPOLAR DISORDERTREATEDWITH ATYPICAL ANTIPSYCHOTIC MONOTHERAPYVERSUS MOOD STABILIZER MONOTHERAPY Jing Y, Guo JJ, Patel NC, Heaton PC, Li H, Kelton CM University of Cincinnati, Cincinnati, OH, USA, University of Georgia, Augusta, GA, USA, Bristol-Myers Squibb Company, Singapore, Singapore OBJECTIVE: To compare health care utilization and cost of children and adolescents with bipolar disorder treated with atypical antipsychotic (ATYP) versus with mood stabilizer (MS) monotherapy. METHODS: We conducted a retrospective cohort study using Pharmetrics administrative claims data from January 1, 1998 to December 31, 2002. The study population included youths (6 < AGE < 19). RESULTS: After matching on the propensity score, 486 subject pairs were retained. On average, ATYP monotherapy subjects had fewer bipolar-related office visits (p = 0.0041), but similar bipolar-related outpatient hospitalization (p = 0.084), bipolar-related days of hospitalization (p = 0.1707), and bipolar-related emergency department visits (p = 1.00). ATYP monotherapy subjects had a lower cost of bipolar-related office visits (p = 0.0246) but higher medication costs (p < 0.0001). There were no cost differences between groups for bipolar-related emergency department visits (p = 0.5477), bipolar-related outpatient hospitalization (p = 0.9817), and bipolar-related inpatient hospitalizations (p = 0.521). Total bipolar-related medical service (p = 0.6501) and general health-related medical service (p = 0.885) costs were also not significantly different between the two groups. CONCLUSION: Compared to patients with MS monotherapy, patients with ATYP monotherapy had fewer bipolar-related office visits and higher medication costs, but similar total bipolarrelated and overall medical service costs.