Abstract
AbstractBlood and plasma viscosity in patients with vascular disease was measured using a rotational cone‐plate viscometer. Increased blood viscosity at moderate (76.8 sec–1) and high (384.0 sec–1) shear rates was found in patients with Bürger's disease. Reduced blood viscosity was noted in patients with livedo vasculitis.Plasma viscosity was significantly increased at low (19.2 sec –1), moderate, and high shear rates in patients with leg ulcer, erythema nodosum, and Bürger's disease, in which blood vessels in the lower dermis and subcutaneous tissue were suspected to be affected. Plasma viscosity at low and moderate shear rates was increased in patients with livedo vasculitis and increased plasma viscosity at low shear rate was noted in patients with superficial vasculitis (anaphylactoid purpura and chronic pigmented purpura).Changes in plasma viscosity correlated well with amounts of γ‐globulin, but not with amounts of fibrinogen.
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