Abstract
A 16 year old girl was evaluated for short stature and delayed puberty. She was noted to be shorter than her twin sister since infancy. Her parents, twin and two other siblings had normal growth and development. Although her twin went through puberty at 12 years of age, she failed to develop any sign of puberty. There were no symptoms of hypothyroidism, adrenal insufficiency, polydipsia or polyuria.
Highlights
A 16 year old girl was evaluated for short stature and delayed puberty
Twin and two other siblings had normal growth and development. Her twin went through puberty at 12 years of age, she failed to develop any sign of puberty
PSIS is a rare disorder of which the exact aetiology is uncertain
Summary
A 16 year old girl was evaluated for short stature and delayed puberty. She was noted to be shorter than her twin sister since infancy. Twin and two other siblings had normal growth and development. Her twin went through puberty at 12 years of age, she failed to develop any sign of puberty.
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