Abstract

Hypothyroidism is a common endocrine disease which occurs when the levels of Thyroid hormones produced by the Thyroid gland are decreased. Here we present a case of a 19-year-old female, who presented with symptoms of hyperprolactinemia, weight gain, unilateral blurring of eyes and headache. Examination findings of the patient were significant for presence of Acanthosis Nigricans and Hirsutism. Rest of the systemic examination was normal. Laboratory investigations revealed Hyperprolactinemia, Hypothyroid profile and dyslipidemia. MRI brain and pituitary done showed findings consistent with Pituitary macroadenoma. Patient was treated along the lines of hypothyroidism with Thyroxine. Follow-up after 3 months showed improvement of her symptoms and disappearance of lesion of MRI scan. This case was a rare presentation of Hypothyroidism. Such unusual and uncommon presentations should be reported and studied in detail to prevent misdiagnosis and provide the correct treatment to the patients.

Highlights

  • Hypothyroidism is a common endocrine disorder in which there is deficiency of Thyroid hormones

  • One third of individuals suffering from primary hypothyroidism have increased levels of prolactin [2]

  • Long standing cases of Primary Hypothyroidism may lead to pituitary hyperplasia

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Summary

Introduction

Hypothyroidism is a common endocrine disorder in which there is deficiency of Thyroid hormones. These individuals may present with symptoms of hyperprolactinemia such as menstrual irregularities, galactorrhea, low bone mass, decreased libido, impotence, infertility, erectile dysfunction [3]. Long standing cases of Primary Hypothyroidism may lead to pituitary hyperplasia. Hypothyroidism should always be considered as a differential in patients presenting with pituitary adenomas, and if a clinician is able to identify the cause of the lesion as hypothyroidism medical treatment should be given rather than opting for surgical treatment options [6].

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Conclusion

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