Abstract
<i>Khaya senegalensis</i> belonging to family Meliaceae. This plant has been used as traditional medicine for several disease such as pain, inflammation, malaria, anemia, diabetic and gastrointestinal diseases. The objective of this study to carry out phytochemical screening, determination of chemical composition and determine antioxidant activity of plant extracts. Many of secondary metabolites were investigated in leaves extract include alkaloids, flavonoids, sterols and saponins while the bark extract includes sterols, triterpines, tannins and saponins. The antioxidant potential of ethanol extract of leaves and bark was determined on the basis of their scavenging activity of the stable 1, 1-diphenyl-2-picryl hydrazyl (DPPH) free radical. Antioxidant activity of leaves extract was higher than bark with (42.69%) and (36.36%) respectively. The quantitative analysis of chemical composition was determined by Gas Chromatography–Mass Spectrometry (GC-MS). A number of bioactive compounds were present in the leaves and bark of <i>K.senegalensis</i>. The highest compound in both extracts represented the reducing sugar 4-O-Methyl mannose (66.47 and 14.73%) in bark and leaves respectively. Fatty acids and phenols were presented in high percentage in both extract include; n-Hexadecanoic acid, 9,12,15-Octadecatrienoic acid, Oleic Acid and Catechol.
Highlights
Traditional medicine is the sum total of knowledge, skills and practices based on the theories, believes and experiences related to different cultures that are meant to maintain health as well as to prevent, diagnose, improve or treat physical and mental illnesses
Plants are composed of secondary metabolites which can be detected through phytochemical screening, which is the process of tracing these secondary metabolites in plants
Phytochemical screening showed that the leaves and bark extracts were rich in chemical constituents
Summary
Traditional medicine is the sum total of knowledge, skills and practices based on the theories, believes and experiences related to different cultures that are meant to maintain health as well as to prevent, diagnose, improve or treat physical and mental illnesses. Activity of Leaves and Bark Extracts from Khaya senegalensis research show the value of herbal medicine in the treating and preventing disease [2]. The extract from the bark of K.senegalensis is characterized by its bitter constituents, is named" calicedrin" in West Africa. It is used extensively as a bittertonic for the treatment of a variety of pro-inflammatory disease. Its bitter constituents, named “calicedrin” in West Africa, characterize the extract from the bark of K.senegalensis. It is used extensively as a bitter tonic for the treatment of a variety of pro-inflammatory disease [4]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
