Abstract
It is our interest to screen Oela europaea L and Ficus carica L leaf extract for total phenolic, flavonoid contents and to evaluate their free radical scavenging and Ferric reducing power (FRAP) using 1,1-diphenyl-2-picrylhydrazyl (DPPH). Data shows that Olea europaea and Ficus carica have strong antioxidant potency to scavenge free radical at an optimal phenolic and flavonoid concentration. Results further suggest a strong correlation between antioxidant activities, phenolic and flavonoid contents. Thus, the screening of Ficus carica and Olea europaea leaf extracts for potential antioxidants as source of drugs for several diseases especially oxidative stress and cancers is illustrated.
Highlights
The Mediterranean flora is remarkable for its diversity and it is a rich source of medicinal plants [1, 2, 3, 4]
Phytochemical screening of Ficus carica L and Oela europaea L leaves: The results of our preliminary phytochemical analysis of Ficus carica L and Olea europaea L leaves extracts were given in Table 1, which revaled the presence of seven known compounds as: Polyphenols, Alkaloids, Flavonoids, Cumarins, Anthocyanins, Trepenoids and Saponins in Ficus carica L leaves extract
The DPPH test of Ficus carica L. showed an increase of the antioxidant activity from (11, 31 ±3, 86%) to (87, 03 ± 0, 15 %) with the increase of extract doses from 50 to 1000 μg/mL
Summary
The Mediterranean flora is remarkable for its diversity and it is a rich source of medicinal plants [1, 2, 3, 4]. Polyphenols [18, 19], flavonoids [19, 20], tannins, organic acids, coumarins, vitamin E and carotenoids have the potency to inhibit the oxidative mechanisms that lead to degenerative diseases [21, 22] These compounds are able to act as antioxidants by different ways: as reducing agents, hydrogen donators, free radical’s scavengers, and singlet oxygen quenchers [23, 24, 25]. Further knowledge is needed about content of polyphenolics, flavonoids, and antioxidant properties of Ficus carica L. and Oela europaea L. leaves For this reason we aimed to determine and compare the phytochemical compounds involved, the antioxidant capacity using free radical scavenging activity (DPPH), ferric reducing antioxidant power (FRAP) assays. To determine their total phenolics (TPC), total flavonoids (TFC) and investigate their relationship with the antioxidant properties of Ficus carica L and Olea europaea L
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