Abstract
Phytochemical analyses were carried out on crude aqueous and ethanol extracts of the root bark of Erythrina senegalensis (RES) to validate its efficacy as a local herb for the treatment of filarial eye lesions. Thin layer chromatograph (TLC), using the solvent system chloroform and methanol (2:1) was done on aqueous and ethanol extracts of the root bark, with 3 mg Ivermectin, a commercial anti-filarial, anthelminthic and ecto-parasitic drug presented as Mectizan ® serving as standard. The analysis indicated the presence of alkaloids, proteins, flavonoids, saponins, tannins and carbohydrates in the root back extract. The relative fraction (Rf) value of Mectizan ® in ethanol extract was 0.942, while that of RES sample was 0.941. The Rf value of Mectizan ® in aqueous extract on the other hand was 0.954, while that of RES sample was 0.952. These results indicate that the root bark of Erythrina senegalensis may possess some anti-filarial as well as anthelminthic and ecto-parasitic activities. International Journal of Natural and Applied Sciences Vol. 2(1) 2006: 12-15
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