Abstract
Plants contain multitude of secondary metabolites conferring them medicinal properties and hence have been employed in curing diseases from time immemorial. Plant based traditional systems of medicines are playing important role in providing health care to large sections of population, especially in developing countries. Ayurveda is a traditional Indian system of medicine which depends on the therapeutic potential of plants. According to Sarangdhara Samhita, a classical Ayurvedic literature, polyherbal drugs in which multiple herbs are combined in a particular ratio have better therapeutic effect and reduced toxicity than monoherbal drugs due to interaction of phytochemicals. Choornam is a type of Ayurveda medicine which is in the form of fine powder of ingredients. Gulgulupanchapala choornam is a polyherbal Ayurvedic medicine used in healing wounds and skin diseases. The ingredients of Gulgulupanchapala choornam are Commiphora wightii, Terminalia chebula, Terminalia bellirica, Phyllanthus emblica, Piper longum, Cinnamomum verum and Elettaria cardamomum. The aim of the present study was to identify the phytochemicals present in Gulgulupanchapala choornam and to assess its antibacterial and antioxidant activities. Agar well diffusion method was used for antibacterial studies of the formulation. The antioxidant potential of the choornam was analyzed by DPPH assay. From the phytochemical analysis it was revealed that carbohydrates, proteins, flavonoids, coumarins, glycosides and phenols were present in ethanol extract of the choornam. The ethanol extract of the choornam inhibited the growth of Staphylococcus aureus and Pseudomonas aeruginosa. The extract also showed dose dependent ability to scavenge DPPH radicals thus establishing its antioxidant potential. Hence it was concluded that the secondary metabolites present in the choornam confers antibacterial and antioxidant potential to it which accounts for its therapeutic ability.
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