Abstract
Turbinaria ornata (Turner) J., tropical brown algae, was found in the South Pacific and Indian Ocean ecosystems. In accordance with recent studies, Turbinaria ornata J. has potent anti-inflammatory effects. Therefore, this study is aimed to explore the biological activities of ethanolic extract of T. ornata J. by analyzing the presence of phytochemical components, antioxidant property, antimicrobial activity, and the wound healing activity. From the results, phytochemical analysis of ethanolic extract of T. ornata J. showed the presence of alkaloids, saponins, oils, total phenolic, and total flavonoid content which were estimated to be 0.683±0.001 Abs and 0.433±0.001 Abs, respectively. Antioxidant activity of the ethanolic extract of T. ornata J. extract showed remarkable DPPH radical scavenging activity of about 58.8% at 200μg/mL and total antioxidant activity of 0.257 Abs at 100μg/mL concentration, as compared to that of their respective controls. The ethanolic extract of T. ornata J. exhibited the maximum zone of inhibition against the clinical pathogens like Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Candida albicans, and Methicillin-resistant Staphylococcus aureus with their potent antimicrobial activity. Wound healing effects of the ethanolic extract of T. ornata J were analyzed by using zebrafish model. The results showed the rapid and significant regeneration of the wounded caudal fin on day 14. Therefore, the preliminary results of this study strongly support that the ethanolic extract of T. ornata J. may be effective in wound healing and regeneration of the wounded tissues.
Highlights
Wound healing is the disruption of the normal biological organs and tissues
This study is aimed to explore the biological activities of ethanolic extract of Turbinaria ornata J by analyzing the presence of phytochemical components, antioxidant property, antimicrobial activity and the wound healing activity
Three types of extracts such as hexane, acetone and methanol was subjected to T. ornata and the results showed that the presence of alkaloids, terpenoids, flavonoids, polyphenols and quinones in hexane extract whereas alkaloids, terpenoids and flavonoids were found to be absent in both acetone and methanol extracts [24]
Summary
Wound healing is the disruption of the normal biological organs and tissues. It regenerate healing in a dynamic, regulated and molecular mechanisms of cells to the wounded areas [1]. Emerging trends in healthy economy amongst the innovations with in the field of wound healing is growing expeditiously [2]. Many researchers widely use natural products for the design of therapeutic drugs and its shows potential wound healing compounds [3]. Seaweeds play an emerging trend in the field of wound healing property against Zebrafish. Earlier studies by researchers have showed that most of the biological therapeutics such as immunomodulatory, stress tolerance, wound healing [5] anti-inflammatory, antiviral, antitumor, antithrombotic, anticoagulant and antioxidant bioactivities have been reported in seaweeds [6]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
