Abstract

Performing vigorous physical activity and taking balanced diet are parts of healthy lifestyles of patients with Familial Hypercholesterolaemia (FH). This study aimed to describe the status of engagement with physical activity and a healthy diet, and their contributing factors. FH patients diagnosed using Dutch Lipid Clinic Network criteria were given validated questionnaires to assess sociodemography, illness characteristics, the status of engagement with physical activity and healthy diet, psychological elements, family support and level of barrier. Significant contributing factors were receiving treatment, level of barrier and intention for behavioural change. The findings may inform the strategy for lifestyle modification of patients with FH.

Highlights

  • Cardiovascular diseases (CVDs) is the leading causes of morbidity and mortality worldwide and Familial Hypercholesterolemia (FH) is one of the important risk factors

  • We found that the lifestyle of our patients with FH associates to their illness condition, i.e. their status of receiving treatment

  • We highlighted that patients with FH who engaged with physical activity are those who are receiving treatment, experiencing a low level of barrier and have the intention to perform physical activities

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Summary

Introduction

Cardiovascular diseases (CVDs) is the leading causes of morbidity and mortality worldwide and Familial Hypercholesterolemia (FH) is one of the important risk factors. In Malaysia, recent National Health and Morbidity Survey (2019) indicated that hypercholesterolemia is one of the significant risks for cardiovascular disease. The prevalence of hypercholesterolemia is 38.1%; indicating one in three Malaysians may have this condition (National Institute of Health, Malaysia ,2020). Other major risk factors are diabetes mellitus, obesity and hypertension. FH is an essential cause of hypercholesterolemia among the Malaysian population. In a recent study among the local community, of the total 4821 participants, 9.1% had severe hypercholesterolemia and the ratio of FH was estimated to be 1:95; which is more common than most that have been reported in European countries (Razman, et al, 2019)

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