Abstract

Come together, right now, over ee: Through the combination of substrates with phosphite-oxazoline or phosphite-thiazoline ligands, we identify one of the few catalytic systems that provide high regio- and enantioselectivities in both enantiomers of the alkylation product for a wide range of hindered and unhindered mono-, di-, and trisubstituted substrates with several carbon nucleophiles.

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