Abstract
Alcohol use can potentiate liver diseases such as hepatitis C and in sufficient quantities can itself cause significant liver disease over time. This chapter will briefly review the importance of alcohol use in liver diseases and difficulties that S.H. Stewart (*) Department of Medicine, University at Buffalo, State University of New York, Buffalo, NY, USA e-mail: ss243@buffalo.edu # Springer Science+Business Media Dordrecht 2016 V.R. Preedy (ed.), Biomarkers in Liver Disease, Biomarkers in Disease: Methods, Discoveries and Applications, DOI 10.1007/978-94-007-7742-2_18-1 1 can arise when clinicians attempt to gather an accurate drinking history in patients with liver disease. The bulk of the chapter focuses on the use of blood phosphatidylethanol (PEth) as an alcohol consumption biomarker in liver disease patients, including validation in this population, potential uses in clinical care and research, and current limitations to its use for these purposes.
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