Abstract
Recordings of the membrane potential from a bursting neuron were used to reconstruct the phase resetting curve (PRC) for a limited set of perturbations. These perturbations were inhibitory synaptic conductance pulses able to shift the membrane potential below the most hyperpolarized level attained in the free running mode. We used a delay embedding method to unfold the limit cycle attractor. For the pulse amplitudes we studied, resetting was independent of amplitude of the perturbation but increased linearly with pulse duration. The predicted and the experimental PRCs show satisfactory agreement. The method was applied to only one pulse per cycle, but our results suggest it could easily be generalized to accommodate multiple inputs, and may ultimately aid us in the analysis of circuits that contain neural oscillators.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
