Abstract
Globular protein solutions of lysozyme in water and added salt are modelledaccording to the Derjaguin–Landau–Verwey–Overbeek (DLVO) theory,in order to determine their fluid–fluid and fluid–solid coexistence lines.Calculations are based on both computer simulations and theoreticalapproaches. Our results indicate that, when the potential parametersare obtained by fitting physical properties directly deducible from eitherstatic or dynamic light scattering data, the fluid–fluid phase coexistencepredictions agree quite well with the experiments. Our description of the solidphase allows only a qualitative reproduction of the experimental solubilityboundaries. The overall accuracy of our predictions is discussed in view of thewell known limitations of the DLVO representation of protein solutions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
