Abstract

The unilateral section of the olfactory peduncle was made in adult albino rats in order to produce axonal and terminal degeneration of the whole system of centrifugal projections. This experiment was carried out with a double purpose. First, to tipify the different structural modes of axonal and terminal degeneration in a correlative light and electron microscopy study. Second, to study the distribution of these central projections to the bulb. The animals were sacrificed by fixation-perfusion 4 to 7 days post-operation and samples of olfactory bulbs were processed as routinely for electron microscopy observation. Thick sections stained with paraphenylenediamine (PPDA)(1) were utilized for phase observation.

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