Abstract
In Vivo Biodistribution Thermoresponsive polymers have found many promising (bio)medical applications, e.g. in situ thermogelling with controlled drug-release, polymer-supported brachytherapy, immunotherapy, and wound dressing. Despite the benefits of thermoresponsive polymers, their biodistribution and fate remained largely unknown, hindering their clinical use. Herein, Ondřej Groborz, Richard Hoogenboom, Martin Hrubý, and co-workers elucidate the pharmacokinetics and fate of thermoresponsive polymers in mice, in article 2201344. Finally, they perform a property-to-pharmacokinetics analysis. Cover art by Tomáš Belloň.
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