Abstract
Background: Ketakyadi Taila is mentioned by Acharya Chakradutta as a drug for the management of Asthigatavata. So for initialization of standardization and assurance of the quality of herbal compounds pharmacognostical and pharmaceutical analysis should be done. Methods: Ketakyadi Taila was subjected to microscopic evaluation for pharmacognostical and physicochemical analysis like Loss on drying, Specific gravity, Saponification, Refractive index, Acid value and High-performance thin layer chromatography (HPTLC). Results: Pharmacognostical study showed the presence of certain identifying characters of all the ingredients of Ketakyadi Taila like Ketaki, Nagbala, Atibala. In pharmaceutical study, preliminary physiochemical analysis showed that loss on drying 0.0925%w/w, specific gravity 0.9174 at room temperature, acid value 4.84 w/w, saponification 185.9 w/w, refractive index 1.4609 and HPTLC showed 4 spots in 254 nm and 3 spots in 366 nm. Conclusions: Pharmacognostical and physico-chemical observations revealed the specific characteristics of all active constituents of Ketakyadi Taila and confirmed the purity and genuinity of the drug.
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