Abstract
We investigate the compaction behavior of the most usual pharmaceutical excipients mixture (placebo) contained lactose monohydrate (LmH), microcrystalline cellulose (MCC), silicum dioxyd (SiO2) and magnesium stearate (MgSt) with combined small- and wide-angle X-ray scattering (SWAXS). [...]
Highlights
[2] Laggner P, Kriechbaum M, Rappolt M, Pabst G, Amenitsch H, Johs A, Lohner K, Zweytick D, Koschuch R, Abuja P
We investigate the compaction behavior of the most usual pharmaceutical excipients mixture contained lactose monohydrate (LmH), microcrystalline cellulose (MCC), silicum dioxyd (SiO2) and magnesium stearate (MgSt) with combined small- and wide-angle X-ray scattering (SWAXS)
Relevant questions of polymorphism in crystalline materials, stability and nanostructure of amorphous states, total inner surface in controlled-release formulations, stability and ageing formulations can be addressed by this technique
Summary
[2] Laggner P, Kriechbaum M, Rappolt M, Pabst G, Amenitsch H, Johs A, Lohner K, Zweytick D, Koschuch R, Abuja P. Pharmaceutical Powder Compaction and Dissolution Analytics by Laboratory Small and Wide Angle X-Ray Scattering (SWAXS)
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