Abstract

The integrity of, and public respect for, clinical research and professional education is endangered by inadequate attention to possible conflicts of interest and conflicts of commitment. All funding sources carry some risk of encouraging “incentive bias,” and no reasonable critics have proposed doing away with pharmaceutical company sponsorship of research and training. Several have urged the pharmaceutical industry to assume a more responsible role in addressing these ethical concerns, even arguing that this industry “should be held to owe a duty of utmost good faith and concern (’fiduciary duty’) for consumers’ safety and well being” (Shimm et al., 1996b). However, the larger burden of responsibility falls on professionals who clearly have a fiduciary duty to place the interests of patients, research subjects, and science above personal welfare.

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