Abstract
hr-NGS detects mosaicism in trophectoderm (TE) biopsies when 10%-90% of cells are abnormal. Mosaic TE biopsies may come from embryos that result from euploid, aneuploid or mosaic pregnancies. Mosaic biopsies have higher risk of miscarrying, lower implantation potential but some may go to term. Mosaic embryos should be classified in between euploid and aneuploid in their priority for transfer. This study aims to determine the rate of euploidy, mosaicism and other abnormalities according to maternal age in a large cohort of embryos for purpose of patient counseling.
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