Abstract
Peritoneal Membrane Transport Characteristics in Uni-PET with Preceding Icodextrin Dwell as Compared to Classic PET with Preceding Glucose Dwell: A Prospective Study
Highlights
Peritoneal equilibration test (PET) is a semi-quantitative assessment of peritoneal membrane transport function in patients on peritoneal dialysis [1] [2] [3]
In subjects on Continuous Ambulatory Peritoneal Dialysis (CAPD) who use icodextrin for long night dwell, it has been recommended that nocturnal exchange be replaced by dextrose dwell whenever PET is to be performed as preceding exchange with icodextrin temporarily increases peritoneal membrane permeability and gives high D/PCr and low D/D0 glucose values
D/D0 at the end of test was more in 7.5% icodextrin Uni-PET (0.34 ± 0.12) as compared to 2.5% dextrose classic PET (0.33 ± 0.11) (Table 2) and (Figure 2)
Summary
Peritoneal equilibration test (PET) is a semi-quantitative assessment of peritoneal membrane transport function in patients on peritoneal dialysis [1] [2] [3]. In subjects on CAPD who use icodextrin for long night dwell, it has been recommended that nocturnal exchange be replaced by dextrose dwell whenever PET is to be performed as preceding exchange with icodextrin temporarily increases peritoneal membrane permeability and gives high D/PCr and low D/D0 glucose values. Whether this temporary change is seen with use of Uni-PET (which involves one hour dwell of 1.5% dextrose followed by 4-hour dwell of 4.25% dextrose) is not known. Conclusion: Peritoneal membrane small solute transport characteristics in Uni-PET with preceding icodextrin
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