Abstract
Peripheral T-cell lymphoma is a rather uncommon non-Hodgkin’s lymphoma with the initial manifestation of spinal cord compression. Herein, we reported a 74-year-old woman with sustained neck pain radiating into the right shoulder and arm and weakness of the right upper extremity. A mass that had invaded the C5 and C6 vertebral bodies, causing a kyphotic curvature and compressing the spinal cord, was discovered with magnetic resonance imaging. The patient then underwent anterior corpectomy at C5 and C6, and reconstruction with a titanic rod and bone cement. The pathology confirmed a diagnosis of peripheral T-cell lymphoma after serial H & E and immunohistochemical staining. She recovered well from her profound neurological deficit. Both chemotherapy and radiotherapy were used postoperatively. Surgical intervention is indicated in these cases to decompress the cord, remove the majority of the tumor mass, stabilize the spine and obtain tissue for pathological diagnosis.
Highlights
Neck and radicular pain are frequent complications and may result from conditions such as herniated intervertebral discs, overgrowth of bone intruding into the spinal canal, spinal stenosis, fracture-dislocation of the spine, infection, or neoplasms [1]
The pathology confirmed a diagnosis of peripheral T-cell lymphoma after serial H & E and immunohistochemical staining
Our objective in presenting this particular case is to highlight the rare presentation of peripheral T-cell lymphoma involving the cervical spine
Summary
Neck and radicular pain are frequent complications and may result from conditions such as herniated intervertebral discs, overgrowth of bone intruding into the spinal canal, spinal stenosis, fracture-dislocation of the spine, infection, or neoplasms [1]. Spinal cord compression as the first presentation of peripheral T-cell lymphomas (PTCLs) has been rarely reported in the literature [2]. Our objective in presenting this particular case is to highlight the rare presentation of peripheral T-cell lymphoma involving the cervical spine
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