Abstract
Aim. To study periodontal tissue status and «lipid peroxidation - antioxidant protection» system in saliva and gingival fluid in petrochemical industry workers.
 Methods. 185 employees of JSC «Experimental Plant Neftechim» were included into the study. Besides the evaluation of dental status saliva and gingival fluid were analyzed for lipid peroxidation products - diene and triene conjugates, malondialdehyde, hydroperoxides and Schiff bases.
 Results. The rate of chronic generalized periodontitis in petrochemical industry workers was 100%, including moderate (47.03%), severe (35.13%) and mild (17.84%) degree. Enhancement of lipid peroxidation and antioxidant defense system activity were detected (in mild and moderate chronic generalized periodontitis) with increasing inflammatory and destructive processes in periodontal tissues. In severe chronic generalized periodontitis reduction in the antioxidant protection activity was observed along with the increasing of lipid peroxidation. Correlation analysis revealed a direct relationship between the periodontal tissue status and «lipid peroxidation - antioxidant protection» system.
 Conclusion. The prophylactic work should be organized among the petrochemical industry employees aiming to decrease risks of diseases; using the obtained data can be used in clinical practice to identify high-risk groups of patients with periodontal pathology.
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