Abstract

Objective To analyze the difference of embryonic development,pregnancy outcomes and safety of the offspring between percutaneous epididymal sperm aspiration-introcytoplasmic sperm injection (PESA-ICSI) and testicular sperm aspiration (TESA-ICSI).Methods The embryonic development and clinical outcomes in both groups of PESA-ICSI and TESA-ICSI were recorded and retrospectively analyzed.Results Both the normal fertilization rate and normal cleavage rate of the PESA group were significantly higher than in the TESA group (P < 0.05).In contrast,no significant difference was detected in high-quality embryo rate,implantation rate,clinical pregnancy,miscarriage rate and birth defects between these two groups (P > 0.05).Conclusion There was no significant difference in pregnancy outcomes and safety of the offspring between PESA-ICSI and TESA-ICSI. Key words: Obstructive azoospermia; Percutaneous epididymal sperm aspiration; Testicular sperm aspiration; Introcytoplasmic sperm injection

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