Abstract
Background: Chronic Spontaneous Urticaria (CSU) is a common allergic skin disease. The etiopathogenesis remains unclear. Recommended therapy is only aimed to reduce and control the symptoms. Vitamin D is a potential immunomodulator that can be used as an alternative therapy of urticaria.
 Objective: This literature study aims to explores various original research literature about the effect of vitamin D in CSU and the mechanism behind that.
 Methods: Narrative review of the literature that searched through three databases with determined keywords, then selected based on inclusion and exclusion criteria.
 Results: There are six literatures with 621 CSU cases. 
 Conclusion: Vitamin D supplementation can reduce the severity of the symptom in CSU patient
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