Abstract
Background: Furadan 3G insecticide is widely used in agriculture sector. Aim: To explore the teratogenic effect on development of the neural tube and cerebellum of the chick embryo. Method: Eighty fertilized eggs were involved in this experiment and incubated until hatching and forty further (the half) were injected with Furadan 3G 11 mg/kg on the first day of the experiment while the other half were referred as control group. The specimen were studied on the day of 5th, 7th, 21st, 2 weeks and 4 weeks of incubation after hatching by preparing a transversal section and staining with M.E. Conclusion: the Furadan 3G interfered the development of cerebellar cortex.
Highlights
Furadan 3G insecticide is widely used in agriculture sector
Eighty fertilized eggs were involved in this experiment and incubated until hatching and forty further were injected with Furadan3G11mg/kg onthefirstdayof theexperiment
Keyword: Furadan 3G, tuba neural, cerebellum while the other half were referred as control group
Summary
Furadan 3G insecticide is widely used in agriculture sector. Aim: To explore the teratogenic effect on developmentof theneural tube and cerebellum of the chick embryo. Akbari telah melaporkan (1987) bahwa perlakuan insektisida Furadan 3G sebanyak 11 mg/gr berat badan yang disuntikkan pada telur ayam ras (Gallu gallus bankvirus) yang telah dibuahi menyebabkan terhambatnya penutupan tuba neuralis di bagian anterior dorsal pada daerah rhombencephalon dari embrio.[1] Tidak menutupnya tuba neraulis tersebut dimulai dengan adanya berkurangnya kepadatan kumpulan sel-sel terutama ujung tuba neuralis.
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