Peculiarities of pulmonary arterial hypertension development in patients with chronic tuberculous pleural effusion

Abstract

Objective. To study the peculiarities of pulmonary arterial hypertension in patients with chronic tuberculous pleural effusion and to evaluate the possibilities of an indirect method of its diagnosis as a screening measure. Materials and Methods. Catheterization of the right heart is considered the "gold standard" for determining pulmonary artery pressure. The known etiopathogenic agents due to pulmonary hypertension cause the development of pulmonary heart, in the presence of which the patient will have an undesirable outcome in the next 3 years. Every year, new patients with pulmonary arterial hypertension are identified. In our opinion, chronic pleurisy affects the development of this complication, which led us to study the problem. Results. Indicators of pulmonary arterial hypertension depended on the stage of chronicity of pleurisy: in the presence of stage II, they were higher. After pleurectomy on the 8th - 10th day, the pressure in the pulmonary artery decreased by 10 - 24 mm Hg. Conclusions. The pressure of pleural effusion on the lung reduces the venous pool and is transmitted to the pulmonary artery, which is accompanied by the release of a number of substances, including serotonin, which cause broncho- and vasospastic reactions. After pleurectomy on the 8th - 10th day, the pressure in the pulmonary artery decreases in most patients, which confirms the effect of the stage of chronic pleurisy on pulmonary hypertension.