Abstract
To analyze the degree of renal impairment of patients with type 2 diabetes mellitus (T2DM) and their healthcare resource use (HCRU) in a Spanish health district using Real World Data (RWD). Non-interventional, cross sectional and population-based study using RWD. The study population included patients with T2DM, age ≥ 18 years. The data corresponding to the 2015-year period was extracted from the information systems of the Clinico-Malvarrosa health district of Valencia (n: 320.000). KDIGO scale was used for stratificating patients with renal impairment. Additionally, patients were stratified according to Clinical Risk Groups (CRG). Explanatory variables: socio-demographic, analytical and clinical parameters (estimated glomerular filtration rate (eGFR), albuminuria and proteinuria), prescription data and HCRU (outpatient contacts, admissions, emergencies). The prevalence of T2DM was 10.76%, average age: 67.75 ± 13.91 years. The distribution according to the level of eGFR reflects that 35.09% and 44.86% were classified in stages G1 (normal or high) and G2 (slightly reduced), respectively. According to the KDIGO scale, 33.81% of the study population had some form of renal impairment. A higher level of correlation between HCRU and eGFR decline was found in comparison to that with albuminuria. Patients with renal impairment had on average about twice as many outpatient contacts and emergency visits (34.76 and 2.08 per year vs. 17.81 and 1.30) and almost three times as many admissions (1.07 vs. 0.37) compared to patients with normal or high eGFR. Chronic kidney disease is highly prevalent in patients with T2DM in Spain and the progression of the disease is correlated to an increase ofHCRU. Analyses with RWD provide additional evidence that reinforce the need of implementing T2DM management strategies that improve not only glycemic control but also limit the progression of the disease and its comorbidities.
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