PD30-07 THE COMBINATION OF BLOOD FLOW VELOCITY AND VASCULAR DIAMETER: THE FLOW INDEX IS BETTER IN THE EVALUATION OF ARTERIOGENIC ERECTILE DYSFUNCTION

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation II (PD30)1 Sep 2021PD30-07 THE COMBINATION OF BLOOD FLOW VELOCITY AND VASCULAR DIAMETER: THE FLOW INDEX IS BETTER IN THE EVALUATION OF ARTERIOGENIC ERECTILE DYSFUNCTION Wei-Lun Huang, Chi-Shin Tseng, Sheng-Yung Tung, Tzung-Dau Wang, Wen-Jeng Lee, Shih-Ping Liu, Hong-Chiang Chang, Yi-Kai Chang, and Yu-Hsiang Yang Wei-Lun HuangWei-Lun Huang More articles by this author , Chi-Shin TsengChi-Shin Tseng More articles by this author , Sheng-Yung TungSheng-Yung Tung More articles by this author , Tzung-Dau WangTzung-Dau Wang More articles by this author , Wen-Jeng LeeWen-Jeng Lee More articles by this author , Shih-Ping LiuShih-Ping Liu More articles by this author , Hong-Chiang ChangHong-Chiang Chang More articles by this author , Yi-Kai ChangYi-Kai Chang More articles by this author , and Yu-Hsiang YangYu-Hsiang Yang More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002031.07AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The dynamic duplex sonography (DUS) measures the blood flow velocity but not the volumetric flow rate of blood, which is the blood volume infused per unit of time. In our experience, some patients with normal DUS result still have vasculogenic erectile dysfunction (ED), indicating that current measurements may be incomprehensive. In our study, a new parameter, the Flow Index (FI), was introduced for evaluating arteriogenic ED. METHODS: Patients receiving DUS and computed tomography angiography (CTA) for evaluation of ED were enrolled. ED was defined based on observed EHS after intracavernous injection of PGE1 during DUS exam. Patients with veno-occlusive dysfunction were excluded. Pelvic arterial (PLA) stenosis and cavernous arterial (CA) stenosis were measured by CTA. The volumetric flow rate of blood was velocity*π*radius2. We defined FI=PSV*(1-arterial stenosis%)2. FI of PLA (FIPLA) and CA (FICA) were calculated. Correlations between parameters were assessed. RESULTS: Eighty-three patients were included. Compared with PSV, FI had better correlations with EHS (Table) and better area under the receiver operating characteristic curve (AUC) for arteriogenic ED (Figure). Compared with patients without arteriogenic ED, patients with arteriogenic ED who had normal DUS had more severe PLA stenosis (62.50% vs 30.00%, P=0.02) and lower FIPLA (12.03 vs 42.17, P=0.01), while the PSV was not different (37.50 cm/s vs 39.90 cm/s, P=0.54). In patients with PLA stenosis, the odds of ED was higher (OR=4.88) and the FI was lower (56.00 vs 67.60, P=0.03 for FICA; 10.22 vs 58.53, P<0.01 for FIPLA), however, the PSV was not significantly different (35.00 cm/s vs 38.25 cm/s, P=0.38). CONCLUSIONS: FI is more comprehensive than PSV in evaluating arteriogenic ED, and PLA patency is one of factors determining penile perfusion. However, PSV may not be suitable for diagnosing arteriogenic ED in patients with PLA stenosis. Source of Funding: none © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e534-e535 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Wei-Lun Huang More articles by this author Chi-Shin Tseng More articles by this author Sheng-Yung Tung More articles by this author Tzung-Dau Wang More articles by this author Wen-Jeng Lee More articles by this author Shih-Ping Liu More articles by this author Hong-Chiang Chang More articles by this author Yi-Kai Chang More articles by this author Yu-Hsiang Yang More articles by this author Expand All Advertisement Loading ...