PD03-05 PHEOCHROMOCYTOMA: IS THERE A ROLE FOR ULTRASONOGRAPHY IN THE SCREENING OF ADRENAL MASS IN HYPERTENSIVE PATIENTS?

Abstract

You have accessJournal of UrologyCME1 Apr 2023PD03-05 PHEOCHROMOCYTOMA: IS THERE A ROLE FOR ULTRASONOGRAPHY IN THE SCREENING OF ADRENAL MASS IN HYPERTENSIVE PATIENTS? Bruno Di Domenico, Gabriel Simoes, Caio de Oliveira, Luiz Gustavo Brandao, Helena Lima, and Marcelo Lima Bruno Di DomenicoBruno Di Domenico More articles by this author , Gabriel SimoesGabriel Simoes More articles by this author , Caio de OliveiraCaio de Oliveira More articles by this author , Luiz Gustavo BrandaoLuiz Gustavo Brandao More articles by this author , Helena LimaHelena Lima More articles by this author , and Marcelo LimaMarcelo Lima More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003220.05AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Pheochromocytomas are catecholamine-producing tumors derivate from chromaffin cells. Their clinical presentation is variable, with arterial hypertension being the most frequent finding and paroxysms (headache, palpitations, and sweating) the most characteristic. Diagnosis is clinical, through the measurement of serum and/or urinary metanephrines and imaging methods. The great challenge is how to identify these patients. It is estimated that 0.1% of hypertensive patients have pheochromocytomas. The hypertension of these patients can be treated surgically by laparoscopic adrenalectomies. The objective of the study was to evaluate the use of ultrasonography as a screening test for pheochromocytoma in hypertensive patients. METHODS: The medical records of all patients who underwent adrenalectomy between 1999 and 2020 were reviewed. Only the patients with a pathologic diagnosis of pheochromocytoma were selected. RESULTS: A total of 29 laparoscopic adrenalectomies were performed in 25 patients, including four bilateral adrenalectomies. The average patient age was 40.2 years old (range 18-66). Ultrasonography was the first exam performed on twenty-nine hypertensive patients in the imaging investigation that showed adrenal masses with a mean diameter of 2.8 cm. After that, all patients underwent computed tomography scanning or magnetic resonance imaging, and meta-[131I]iodobenzylguanidine (131I-MIBG) whole-body scintigraphy before adrenalectomy. Measurements of plasma metanephrines and/or urinary catecholamines were high in all patients. Although abdominal ultrasonography usually has low sensitivity and specificity, it was fundamental to identifying patients with adrenal mass and proceeding with the investigation. CONCLUSIONS: Ultrasonography was an efficient method for screening investigation of pheochromocytoma in the hypertensive population and is considered a safe, low-cost and fast imaging exam. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e76 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Bruno Di Domenico More articles by this author Gabriel Simoes More articles by this author Caio de Oliveira More articles by this author Luiz Gustavo Brandao More articles by this author Helena Lima More articles by this author Marcelo Lima More articles by this author Expand All Advertisement PDF downloadLoading ...