Abstract
Fluid resuscitation remains the cornerstone of acute burn management. Adequate fluid administration is critical to preventing burn shock and other complications. The Baxter formula (4cc/kg/TBSA) has been used to estimate resuscitation fluid requirements for over 40 years. However, several studies suggest that the Baxter formula does not accurately predict fluid requirements in patients with larger burns. and that patients today are receiving more fluid per-percent TBSA than in the past. The purpose of this study was to examine the volumes of fluid administered to a cohort of severely burned patients and to identify clinical variables that may fluid requirements. This study was carried out as part of the multicenter study Inflammation and the Host Response to Injury. Patient data was prospectively collected at five institutions and recorded in the online trial database. Baseline patient and injury variables analyzed included: age, TBSA, body mass index (BMI), medical comorbidities, inhalation injury, time...
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