Abstract

Background: Infertility is defined as the failure of a couple to conceive after one year of regular sexual intercourse. The malefactor is responsible for at least 50% of cases of failure to conceive. Semen analysis remains the cornerstone in the preliminary investigation of male factor infertility. This study aimed to evaluate seminal fluid parameters in the male partners of infertile couples. Materials and Methods: This retrospective study was conducted in the Department of Pathology, Patan Academy of Health Sciences, Patan hospital, Nepal between December 2019 and January 2020. All the 243 specimens were processed and analyzed according to WHO guidelines on semen analysis. Results: Present study included a total of 243 semen samples, aged between 20-63 years with a mean age of 32.0 years. Normozoospermia was observed in (26.3%). The most common abnormalities found in this study were asthenozoospermia (25.5%), oligospermia (19.3%), azoospermia (6.5%), and teratozoospermia. Conclusions: Semen analysis remains a keystone in assessing male factor infertility in developing countries like Nepal. However, needs further evaluation to establish possible etiologies of male infertility.

Highlights

  • According to the International Committee for Monitoring Assisted Reproductive Technology, World Health Organization (WHO), infertility is a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.[1]

  • This study aimed to evaluate seminal fluid parameters in the male partners of the infertile couples presenting to the infertility clinic of Patan Hospital

  • Routine semen analysis is still the gold standard for assessing male factor infertility in developing countries like Nepal, but it is vital to recognize its limitations in terms of collection, processing, and interpretation, as well as biological variance in the parameters and a lack of information on sperm activity

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Summary

Introduction

According to the International Committee for Monitoring Assisted Reproductive Technology, World Health Organization (WHO), infertility is a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.[1] Infertility is a major clinical and public problem affecting the life of the couple. Infertility is defined as the failure of a couple to conceive after one year of regular sexual intercourse. Semen analysis remains the cornerstone in the preliminary investigation of male factor infertility. This study aimed to evaluate seminal fluid parameters in the male partners of infertile couples

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