Abstract
To describe the pattern of clinical euthyroidgoitre in a tertiary care unit in Sri Lanka before and after iodination of salt in Sri Lanka. We reviewed our thirty-one year computerised database of patients with goitres, spanning iodination in 1995. Prevalence of euthyroid clinical simple diffuse goitre did not reduce during the first thirteen years (p=0.822). However, it reduced in the latter four years from 2008 to 2011. There is significant reduction of prevalence in the younger age groups (p<0.001). A significant reduction of nodular change was observed in all groups within seven years after iodination (p<0.001). There was a significant reduction in the prevalence of clinical nodularity in the post-iodination era in all age groups. Reduction in prevalence of clinical euthyroid simple diffuse goitre was observed only during the period 2008-2011.
Highlights
The implementation of compulsory iodination of salt as a national policy in 1995 has changed the pattern of thyroid malignancy in Sri Lanka [1]
That salt iodination can affect the pattern of benign euthyroid disease (BETD) is well documented [2,3,4]
Female to male ratio was higher in the post iodination era (Table 1 and Figure 1)
Summary
The implementation of compulsory iodination of salt as a national policy in 1995 has changed the pattern of thyroid malignancy in Sri Lanka [1]. That salt iodination can affect the pattern of benign euthyroid disease (BETD) is well documented [2,3,4]. Most studies from Sri Lanka which looked at prevalence of goiters show a reduction in prevalence of Grade I BETD after iodination. The surveys detected very few clinically significant (Grade II- visible goitre and above). There has been no published data on the change in prevalence of clinical goitre in Sri Lanka.We analysed a database of patients with BETD over a thirty one year period, which spans iodination of salt, to see if the changes in the patterns of presentation are salutary
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