Patient-reported outcomes with a personalized follow-up program after lung cancer resection: A single-center randomized controlled trial.

BACKGROUND Postoperative lung cancer patients often experience frequent symptoms, multisystem dysfunction, reduced physical strength and activity levels, significantly impacting their quality of life. Continuity of care is crucial for these patients. Information technology based on patient-reported outcomes can efficiently assess symptoms and improve health. OBJECTIVE This study aims to determine the impact of a personalized follow-up program based on patient-reported outcomes on the quality of life and self-management efficacy of postoperative lung cancer patients, and to explore their compliance and perspectives on its use. METHODS A parallel-arm randomized controlled trial with an assessor-blinded design and repeated measures.Participants were recruited from the inpatient oncology department of a university-affiliated hospital in Shanghai, China. A total of 240 lung cancer patients who had undergone radical lung cancer surgery and were discharged participated in the postoperative follow-up study.Participants were randomly assigned to either the experimental or the control groups. Patients in the experimental group received a personalized follow-up program based on patient-reported outcomes. This program incorporated the MD Anderson Symptom Inventory with set alarm thresholds, enabling nurses, supported by a multidisciplinary team, to accurately assess and identify individual needs and provide tailored interventions. The control group received only the usual telephone follow-up. Baseline data (T0) were collected before the intervention (on the day of discharge), and quality of life, self-efficacy, and compliance were measured at 2 weeks (T1), 4 weeks (T2), and 12 weeks (T3) post-discharge. Additionally, patients in the experimental group were asked to share their experiences and perspectives on the intervention through open-ended questions. RESULTS The difference in quality of life between the experimental and control groups was significant (Wald X²=5.204, P=.023), with the experimental group showing significantly better quality of life at T2 compared to the control group (t=2.515, P=.013). No significant differences were observed at T0, T1, and T3. Both groups showed improvements in quality of life at all post-test time points (Wald X²=574.167, P < .001), and the interaction between group and time was not statistically significant (Wald X²=2.354, P=.308). Regarding self-management efficacy, Generalized Estimating Equations results indicated a significant difference between the experimental and control groups (Wald X²=6.573, P=.010), with the experimental group showing significantly higher self-management efficacy at T2 and T3 compared to the control group (t=3.024, P=.003; t=2.214, P=.028). No significant differences were observed at T0 and T1. Both groups showed improvements in self-management efficacy at all post-test time points (Wald X²=301.390, P < .001), and the interaction between group and time was not statistically significant (Wald X²=3.971, P=.137). A thematic analysis of the experimental group's feedback on device usage revealed six major categories. CONCLUSIONS This study shows that for patients after lung cancer surgery, it is appropriate, acceptable, feasible and attractive to rely on WeChat mini-programs to carry out follow-up projects based on patient-reported outcomes. This program has improved the postoperative quality of life and self-management efficacy of lung cancer patients. Evidence transformation, staff training, patient-reported outcome tool setting, and multidisciplinary cooperation are effective strategies to ensure implementation. CLINICALTRIAL Registered in ClinicalTrial.gov on 13 March 2024(NCT06483295), began recruiting participants subjects on 14 March, 2024.

BackgroundWith a focus on postoperative dysfunctions that may occur after maxillofacial tumor resection and the difficulties faced during home rehabilitation, we developed a mobile health app based on nurse-patient cooperation. The app extends rehabilitation care from hospital to home with the help of artificial intelligence, Internet of Things, and other technologies, thus helping patients to better carry out their home functional rehabilitation and meet their health needs.ObjectiveThe primary objective of this quasi-experimental study is to evaluate the impact of the Intelligent Home Rehabilitation Care Platform on the quality of life, self-management, and functional impairment in patients with oral and maxillofacial head and neck tumors. We aim to determine whether the intervention through this platform can lead to significant improvements in these areas compared with traditional postdischarge care methods.MethodsIn this study, patients with oral and maxillofacial head and neck tumors who had undergone surgery were recruited from allied hospitals in the Yangtze River Delta region, divided into an experimental group (n=138) and a control group (n=123), and received either the Intelligent Home Rehabilitation Care Platform intervention or the conventional health care and guidance, respectively. The intervention lasted 3 months, and the patients’ quality of life, self-management efficacy, and improvement in dysfunction were assessed at 1 week (baseline), 1 month (T1), and 3 months (T2) postoperatively. SPSS software (IBM Corp) was used to perform the chi-square test, rank sum test, t test, repeated-measures ANOVA, and generalized estimation equation for data analysis.ResultsWe analyzed the effects of the quality of life and self-management using the generalized estimating equation method. The generalized estimating equation results showed that after adjusting for age, sex, pathological histology, cancer stage, and primary site, the intervention group had a significantly higher improvement in quality of life than the control group at the T2 (regression coefficient, β=−68.020, 95 % CI −116.639 to −19.412; P=.006) stage. The degree of improvement in self-management efficacy was significantly higher in the T1 (regression coefficient, β =−7.030, 95 % CI −9.540 to −4.520; P<.001) and T2 (regression coefficient, β =−13.245, 95 % CI −16.923 to −9.566; P<.001) stages than in the control group. The results of repeated-measures ANOVA and rank sum test showed that the experimental group showed improvements in shoulder function, dysphagia, and trismus after mHealth intervention; however, the differences were not significant.ConclusionsThe Intelligent Home Rehabilitation Care Platform interventions can effectively enhance patients’ self-management efficacy, improving quality of life and facilitate recovery from dysfunctions. Therefore, mHealth may be used in oncology care to provide smarter home self-care for patients.

Is Video-Assisted Thoracic Surgery Lobectomy Better? Quality of Life Considerations

1: A Randomized Controlled Trial of Office Polyp Treatment (OPT) for Abnormal Uterine Bleeding

BackgroundThere have been few studies on the relationship between oral status and postoperative pneumonia (POP) in patients with lung cancer, and whether improving their oral condition assists with a lower incidence of POP before lung cancer surgery remains controversial. This retrospective study was conducted by a stomatologist to assess the effect of controlling oral pathogenic bacteria of patients with lung cancer to prevent POP.MethodsA total of 235 patients with lung cancer who underwent lobectomy by open thoracotomy between July 2015 and December 2018 were selected and given the choice of being in the experimental or control group. A total of 122 participants in the experimental group received professional oral plaque control, and 113 participants in the control group did not receive plaque control. All clinical data of participants in both groups were retrospectively studied to determine the incidence of POP at the thirtieth day of discharge from hospital.ResultsEight in the experimental group and six in the control group were excluded from the study. It was found that four of 114 patients suffered from POP in the experimental group (incidence = 3.51%). A total of 17 of 107 patients in the control group had pulmonary infection (incidence = 15.89%). Odds ratio was 0.19. The incidence of POP in the experimental group was significantly lower than that of the control group (P < 0.05).ConclusionsProfessional oral plaque control is associated with a lower incidence of POP following lung cancer surgery and is therefore a favorable factor for preventing POP, and should be carried out before the surgical treatment of lung cancer.Key pointsProfessional oral plaque control was associated with a lower incidence of POP following lung cancer surgery, and it is recommended this should be carried out before the surgical treatment of lung cancer.

Introduction. Diabetes Mellitus (DM) is a chronic disease that requires individual ability of patients to adhere treatment of the disease recommended by doctors. The purpose the study was to analyze the effect of diabetes empowerment education to self empowerment and quality of life of patients with type 2 DM.Method. This study used quasy experiment design with non randomized control group pretest posttest design. Total sampel was 32 respondents divided into control group and experiment group, sample recruited by purposive sampling. Data were collected using questionnaire with DES (Diabetes Empowerment Scale) and DQoL (Diabetes Quality of Life). Data were then analyzed using Wilcoxon Sign rank test and Mann Whitney with level of significance of 0,05.Result. The results showed that there were differences in self empowerment and quality of life of patients with type 2 DM after intervention. Mann Whitney analysis result`s showed that there are differences in self empowerment between control and experiment groups (p = 0,029) and there was a difference in the quality of life between control and experiment groups (p = 0,022). It can be referred from it that DEE influences self empowerment and quality of life of type 2 DM patients.Discussion. It can be concluded that diabetes empowerment education increasing selfempowerment and quality of life of patients with DM type 2. Keywords: diabetes, education, self empowerment, quality of life, DEE, HPM

Introduction: Diabetes Mellitus (DM) is a chronic disease that requires individual ability of patients to adhere treatment of the disease recommended by doctors. Patient should be able to manage the diabetes to prevent complications by maximizing existing aspects within themselves to determine the best option available. The purpose the study was to analyze the effect of diabetes empowerment education to self empowerment and quality of life of patients with type 2 DM at the Puskesmas Bendo Kediri. Method: This study used quasy experiment design with non randomized control group pretest posttest design. Total sampel was 32 respondents divided into control group and experiment group, sample recruited by purposive sampling. Data were collected using questionnaire with DES (Diabetes Empowerment Scale) and DQoL (Diabetes Quality of Life). Data were then analyzed using Wilcoxon Sign rank test and Mann Whitney with level of significance of 0,05. Result: The results showed that there was a differences in self empowerment and quality of life of patients with type 2 DM after intervention. Mann Whitney analysis result`s showed that there are differences in self empowerment between control and experiment groups (p = 0,029) and there was a difference in the quality of life between control and experiment groups (p = 0,022). It can be referred from it that DEE influences self empowerment and quality of life of type 2 DM patients. Discussion: It can be concluded that diabetes empowerment education increasing selfempowerment and quality of life of patients with DM type 2. Further studies should using more objective parameters such as changes in blood sugar levels, hemoglobin A1C values to evaluate the effect of diabetes empowerment education on self-empowerment and quality of life of patients with DM. Keywords: diabetes, education, self empowerment, quality of life, HPM,DEE

Introduction: Diabetes Mellitus (DM) is a chronic disease that requires individual ability of patients to adhere treatment of the disease recommended by doctors. Patient should be able to manage the diabetes to prevent complications by maximizing existing aspects within themselves to determine the best option available. The purpose the study was to analyze the effect of diabetes empowerment education to self empowerment and quality of life of patients with type 2 DM at the Puskesmas Bendo Kediri.Method: This study used quasy experiment design with non randomized control group pretest posttest design. Total sampel was 32 respondents divided into control group and experiment group, sample recruited by purposive sampling. Data were collected using questionnaire with DES (Diabetes Empowerment Scale) and DQoL (Diabetes Quality of Life). Data were then analyzed using Wilcoxon Sign rank test and Mann Whitney with level of significance of 0,05. Result: The results showed that there was a differences in self empowerment and quality of life of patients with type 2 DM after intervention. Mann Whitney analysis result`s showed that there are differences in self empowerment between control and experiment groups (p = 0,029) and there was a difference in the quality of life between control and experiment groups (p = 0,022). It can be referred from it that DEE influences self empowerment and quality of life of type 2 DM patients. Discussion: It can be concluded that diabetes empowerment education increasing selfempowerment and quality of life of patients with DM type 2. Further studies should using more objective parameters such as changes in blood sugar levels, hemoglobin A1C values to evaluate the effect of diabetes empowerment education on self-empowerment and quality of life of patients with DM.

To investigate the effects of refined nursing strategies on postoperative quality of life, pain level, psychological condition, and other rehabilitation training of patients with cervical spondylosis. This study is a retrospective study, and 500 patients with cervical spondylosis admitted to our hospital from April 2022 to June 2023 were selected as the study objects. They were divided into a control group (250 cases) and an experimental group (250 cases) according to whether they received personalized intensive care. The control group received standard nursing care, while the experimental group was given personalized, high-quality nursing care. The refined nursing strategy comprises individualized rehabilitation training plans, psychological support, nutritional counseling, and pain management. Indicators such as pain level, cervical spine function, quality of life, complication statistics, and nursing satisfaction were employed to evaluate the clinical efficacy of 2 nursing methods. In the pain assessment, patients in the experimental and control groups had pain scores of (1.98 ± 0.84) and (5.78 ± 0.63), respectively, after the nursing intervention. The reduction in pain for patients in the experimental group was highly significant (P < .05) compared to pre-nursing care. Six months after the commencement of healthcare, the cervical spine function scores of the experimental and control groups were (93.36 ± 4.74) and (82.68 ± 5.42), respectively. Moreover, the cervical spine function recovery of the experimental group was deemed significant. The experimental group exhibited a lower probability of complications compared to the control group. Additionally, the quality of life was significantly higher in the experimental group than in the control group (P < .05). Improvement time and healing time were significantly shorter in the patients of the experimental group in comparison to the control group. In terms of nursing satisfaction, the experimental group had a significantly higher satisfaction rate of 87.57% than the control group (P < .05). The refined nursing strategy significantly improved the speed and quality of patients' functional recovery. Additionally, the implementation of personalized and comprehensive nursing techniques during postoperative treatment for cervical spondylosis resulted in a significant improvement in patient's quality of life and satisfaction with the treatment process.

The effect of a web-based self-care instruction on symptom experience and quality of life in living liver donors: A randomized controlled trial

This study examined the impact of a virtual reality intervention program based on psychological needs on behavioral and psychological symptoms, apathy, and quality of life (QOL) in patients with dementia or mild cognitive impairment living in nursing facilities. This study is nonequivalent control group pretest-posttest design of quasi-experimental study. The study collected data from November 18, 2020 to July 24, 2021 from patients with dementia or mild cognitive impairment (30 in the experimental group and 30 in the control group) at three nursing facilities in G city using self-reporting and caregiver-informant reporting methods. The analysis employed the chi-square test, Fisher's exact test, paired t-test, independent t-test, Wilcoxon signed rank test, Mann-Whitney U, repeated measures ANOVA, GEE, using SPSS/WIN 27.0. The severity of behavioral and psychological symptoms (Wald χ² = 2.68, p = .102) and the care burden of caregivers (Wald χ² = 1.72, p = .190) were not significant and was no significant time and group interaction effect (Wald χ² = 0.63, p = .426, Wald χ² = 0.52, p =. 471). The difference in apathy and QOL score were statistically significant for the group-time interaction (F = 43.65, p < .001; F = 4.35, p = .041). The virtual reality intervention program of this study shows a positive effect on the apathy reduction and QOL of patients with dementia or mild cognitive impairment residing in nursing facilities.

Previous studies have demonstrated that the Lee Silverman Voice Treatment-BIG (LSVT-BIG) program can improve motor functions such as balance and gait in Parkinson's disease (PD) patients. However, no study has investigated the effects of a task-based LSVT-BIG intervention on hand function, psychological function, and quality of life in PD patients. Herein, we investigate the effects of a task-based LSVT-BIG intervention, which reflects the needs of PD patients, on hand function, activity of daily living (ADL), psychological function, and quality of life. A total of 14 PD patients were enrolled and randomly assigned to the experimental or control group. The experimental group performed 30 minutes of conventional occupational therapy and 40 minutes of the task-based LSVT-BIG program. The control group performed 30 minutes of conventional occupational therapy and 40 minutes of relaxation and stretching. Both groups underwent the respective interventions once a day 5 times a week for 4 weeks. As a result of the study, the experimental group showed improvement in hand function in both the dominant and nondominant hand, and the control group showed improvement only in the nondominant hand (p < .05). ADL was significantly improved in both groups, but the experimental group showed a more statistically significant difference than the control group (p < .05). Depression and anxiety were significantly decreased in both the experimental group and the control group, and in particular, in the case of anxiety, there was a more statistically significant difference in the experimental group (p < .05). In the case of the experimental group, there was a significant improvement in quality of life in all items, and in the control group, except for the social function item (p > .05), there was a significant improvement in other items (p < .05). The results of this study suggest that the task-based LSVT-BIG program, which consists of activities desired by the participants, may be an effective intervention to improve hand function, ADL, psychological function, and quality of life in PD patients.

Hemodialysis is frequently used as a primary treatment for individuals with end-stage kidney disease (ESKD), and it significantly impacts the quality of life in adolescents undergoing this procedure. Providing a hemodialysis education to these patients is a valuable strategy for enhancing their well-being. The aim of the study is to assess the effect of the video-assisted educational program on the quality of life among adolescents undergoing hemodialysis in Palestine. This study employed a quasi-experimental design, a pre-test-post-test interventional study, involving a sample of 68 adolescent patients between the ages of 13 and 18 diagnosed with ESKD. The quality of life level was assessed in both groups using an Arabic version of the Pediatric Quality of Life Inventory™ version 3.0 ESKD Module survey. The study was conducted at the dialysis units in four hospitals associated with Augusta Victoria Hospital, An-Najah University Hospital, Palestine Medical Complex/Ramallah, and Beit Jala (Al Housain) Hospital. The study involved providing tailored face-to-face educational sessions with video assistance to the experimental group, while the control group received regular face-to-face education. The Generalized Estimating Equation analysis revealed no significant differences in quality of life between the experimental and control groups over time, across pre-test, post-test, and follow-up periods (p ≥ 0.05). However, within the experimental group, there was a significant improvement in total quality of life scores between the pre-test, post-test, and post-test follow-up (p ≤ 0.001), although the difference between the pre-test and follow-up approached significance but was not statistically significant (p = 0.056). In contrast, the control group showed significant differences in quality of life across the pre-test, post-test, and follow-up time points (p ≤ 0.05). Implementing suitable interventions can potentially enhance the quality of life for individuals undergoing hemodialysis. Consequently, we suggest using video-based education as a cost-effective, uncomplicated, and engaging approach for educating hemodialysis patients.

Pulse therapy with vincristine and dexamethasone for childhood acute lymphoblastic leukaemia (CCCG-ALL-2015): an open-label, multicentre, randomised, phase 3, non-inferiority trial.

The volume-outcome relationship in lung cancer surgery: The impact of the social determinants of health care delivery.