Abstract
The Bunyavirus genus of the family Bunyaviridae is named after Bunyamwera virus (Smithburn et al., 1946), and includes over 150 individual viruses classified in several serogroups. In addition to their serological relationship, members of the genus have been grouped together because of similar molecular features (Bishop and Shope, 1979; Bishop et al., 1980; Gonzalez-Scarano and Nathanson, 1995; see Chapters 1 and 2 in this volume). Almost all of the viruses in the Bunyavirus genus can be transmitted by mosquitoes to a large number of vertebrate hosts. From the standpoint of human infections, the viruses in the California serogroup are the most relevant, as they have been associated with influenza-like illnesses in central Europe and are an important cause of encephalitis in the midwestern United States. However, other members of the genus are of veterinary importance, and there have been scattered reports of febrile illnesses in humans associated with several other viruses in the genus (Parsonson and McPhee, 1985; Shope, 1985). Table I lists the members of the genus that are known to cause disease in either humans or animals.
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