Abstract

Recent years have seen the discovery of the cause of AIDS, the virus HIV1. The leading articles of this issue of Serodiagnosis and Immunotherapy concern antigen detection, antibody detection and immunotherapy in this disease. Advances in the academic knowledge of the virus have been associated with an increase in the number of patents which have been filed. This article contains the results of a computerised search of the patent literature. A selection of the patents have then been summarised and reviewed in depth. The patents which have been lodged in connection with the virus vary greatly in their complexity. They span a spectrum from simple patents designed to cover antibody detection, to very much more complex patents where individual viral antigens have been cloned and sequenced. The quality of the patents is highly variable. There are confused patents based on recombinant technology, whose validity one must seriously question, which can be contrasted with very simple patents which cover accurately and precisely one aspect of the infection. It is difficult to estimate the value of the patents as much of the material contained would be obvious when the previous literature on the subject has been read. In this opening introduction, a very brief summary of 23 of the most well thought out and impressive patents will be presented. This will be followed by a list of the patents applied for and an in-depth review of individual patents. These will be under appropriate headings.

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