Abstract
The tableting properties for fermented spray dried jackfruit (FJP) and microcrystalline cellulose (MCC) powders were studied. 25% FJP + 75% MCC, 50% FJP + 50% MCC and 75% FJP + 25% MCC binary powder mixtures were compacted into tablet form at various compaction pressures ranging from 15.1 to 73.8 MPa. The properties were compared to pure FJP and MCC tablets. The addition of MCC resulted in a higher particle size and the increased in the plastic work of the tablet. The best ratio of FJP-MCC binary tablet was found to be at 25% FJP + 75% MCC where the tablet showed the highest tensile strength. In conclusion, the addition of MCC to FJP improved the compaction characteristics and the tablet mechanical strength.
Highlights
Jackfruit (Artocarpus heterophyllus Lam) is a nonseasonal fruit commonly found in Asia (Ranasinghe et al, 2019)
It was found that the microcrystalline cellulose (MCC) particles were significantly larger (P < 0.05) than the spray-dried fermented jackfruit pulp (FJP) particles, about 5.6 times larger in terms of their median size, d50
With the further addition of MCC to 50% w/w MCC + 50% fermented jackfruit pulp spray-dried powder (FJP), the resulting binary powder mixture particle median size significantly (P < 0.05) displayed an exponential increase of about 3.2 times compared to the case when just 25% w/w MCC was added to the formulation
Summary
Jackfruit (Artocarpus heterophyllus Lam) is a nonseasonal fruit commonly found in Asia (Ranasinghe et al, 2019). A previous study showed the potential of fermented jackfruit pulp containing relatively higher total phenolics content and antioxidant activities (Aziz et al, 2017). In this previous study, the jackfruit pulp was fermented by either adding yeast or acetic acid bacteria for seven days at 300C. The active ingredient would be added with various types of excipients to improve the active ingredient compaction characteristics. This has been extensively studied by previous researchers using various
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