Participation in research as a means of improving quality of care: the role of a principal investigator in multicentre clinical trials

Abstract

Key content A doctor’s duty to reduce uncertainty in the provision of care requires their participation in well‐developed and ethically approved clinical trials. Compared to non‐participation, collaboration in a clinical trial improves the quality of care of women. Successful recruitment into multicentre trials is achieved through enthusiastic involvement of several principal investigators (PIs). Allocation of NHS patient care costs for clinical research supports those engaged in recruiting women into studies. Consultants need to acquire basic mandatory research training for the role as a PI leading research. An awareness of support mechanisms locally, regionally and nationally, such as NIHR Clinical Research Network, aids in the execution of PI duties. PI contribution to research is a recognised professional and personal development activity and forms an integral part of appraisal, revalidation and clinical excellence award scheme. Learning objectives To recognise the added benefits to care of women through participation in research. To ascertain the roles and responsibilities of a PI engaged in a multicentre clinical trial. To identify ways to overcome barriers and avail support mechanisms offered to consultants in their role as PI. To increase awareness of the various means by which consultants can attain recognition and rewards for their responsibility as PI. Ethical issues It is the responsibility of the principal investigator to ensure that all eligible women are offered the opportunity to participate in clinical studies.